Student’s Design Helps Piece Together Parts Of The Alzheimer’s Puzzle

The point is that Alzheimer does not have a clear boundary. It's all about how the brain processes information. Studying the extreme conditions can reveal the mechanisms that are working in "normal" conditions. Normal is a statistical construct. Not a real thing.

Student’s Design Helps Piece Together Parts Of The Alzheimer’s Puzzle:
"ScienceDaily (June 29, 2009) — A Kingston University design student has turned his coursework into a budding business venture, launching a jigsaw puzzle ideal for people living with dementia.

Ben Atkinson-Willes, 22, who is completing a degree in product and furniture design at Kingston University in South West London this year, was inspired to use his skills to create a specially-designed activity puzzle after his granddad was diagnosed with Alzheimer’s disease."

And

Measuring Brain Atrophy In Patients With Mild Cognitive Impairment
ScienceDaily (June 28, 2009) — Scientists at the University of California, San Diego School of Medicine have shown that a fully automated procedure called Volumetric MRI – which measures the "memory centers" of the brain and compares them to expected size – is effective in predicting the progression from mild cognitive impairment (MCI) to Alzheimer's disease. The procedure can be readily used in clinics to measure brain atrophy, and may help physicians to predict decline in MCI patients.